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Publications

Lab member names are bolded.

2026

R. Sandilya, S. Perez, C. Lynch, L. Victoria, B. Zebley, D. M. Buchanan, M. T. Bhati, N. Williams, T. J. Spellman, F. M. Gunning, C. Liston, L. Grosenick (2026).

Contrastive Diffusion Alignment: Learning Structured Latents for Controllable Generation

International Conference on Machine Learning (ICML)

arXiv ★ Top-3 AI/ML venue

L. Grosenick, C. Liston (2026).

Multimodal Representation Learning for Parsing Biological Heterogeneity in Psychiatric Neuroimaging

Biological Psychiatry

C. J. Lynch, M. Chang, I. Elbau, E. M. Gordon, T. O. Laumann, J. Du, Z. Ladwig, M. Lueckel, D. C. Perez, I. Summerville, J. Chou, M. Johnson, C. Ho, N. Manfredi, P. Nilchian, N. Solomonov, E. Goldwaser, T. Ng, S. Moia, C. Caballero-Gaudes, J. Downar, F. Vila-Rodriguez, E. Gregory, Z. J. Daskalakis, D. M. Blumberger, K. Kay, D. Buchanan, N. Williams, M. T. Bhati, J. Clauss, B. Zebley, L. W. Victoria, J. D. Power, L. Grosenick, F. M. Gunning, C. Liston (2026).

Objective Quality Assessment for Precision Functional MRI Data

Neuron

2025

M. Ajirak, O. Bein, E. B. Bowen, D. Kanellopoulos, A. Falk, F. M. Gunning, N. Solomonov, L. Grosenick (2025).

Learning to Route: Per-Sample Adaptive Routing for Multimodal Multitask Prediction

Advances in Neural Information Processing Systems (NeurIPS)

Paper ★ Top-3 AI/ML venue

Q. Zhao, L. Milecki, A. Kuceyeski, , L. Grosenick, T. Brumback, A. Pfefferbaum, E. V. Sullivan, K. M. Pohl (2025).

Socioemotional and Executive Control Mismatch in Adolescence and Risks for Initiating Drinking

JAMA Network Open

I. Kauvar, E. B. Richman, T. X. Liu, C. Li, S. Vesuna, A. Chibukhchyan, L. Yamada, A. Fogarty, E. Solomon, E. Y. Choi, L. Mortazavi, G. Chau Loo Kung, P. Mukunda, C. Raja, D. Gil-Hernández, X. Patron, X. Zhang, J. Brawer, S. Wrobel, Z. Lusk, D. Lyu, A. Mitra, L. Hack, L. Luo, L. Grosenick, P. van Roessel, L. M. Williams, B. D. Heifets, J. M. Henderson, J. A. McNab, C. I. Rodr\'\iguez, V. Buch, P. Nuyujukian, K. Deisseroth (2025).

Conserved brain-wide emergence of emotional response from sensory experience in humans and mice

Science

M. Ajirak, T. Adali, S. Sanei, L. Grosenick, P. M. Djurić (2025).

Exploring synergies: Advancing neuroscience with machine learning

Signal Processing

2024

I. Osafo Nkansah, N. Gallagher, R. Sandilya, C. Liston, L. Grosenick (2024).

Generalizing CNNs to graphs with learnable neighborhood quantization

Advances in Neural Information Processing Systems (NeurIPS)

Paper Code PDF ★ Top-3 AI/ML venue

M. Hargrave, A. Spaeth, L. Grosenick (2024).

EpiCare: A reinforcement learning benchmark for dynamic treatment regimes

Advances in Neural Information Processing Systems (NeurIPS)

Paper Code PDF ★ Top-3 AI/ML venue

M. Ajirak, I. Elbau, N. Solomonov, L. Grosenick (2024).

Discrete representation learning for multivariate time series

2024 IEEE European Signal Processing Conference (EUSIPCO)

C. J. Lynch, I. G. Elbau, T. Ng, A. Ayaz, S. Zhu, D. Wolk, N. Manfredi, M. Johnson, M. Chang, J. Chou, I. Summerville, C. Ho, M. Lueckel, H. Bukhari, D. Buchanan, L. W. Victoria, N. Solomonov, E. Goldwaser, S. Moia, C. Caballero-Gaudes, J. Downar, F. Vila-Rodriguez, Z. J. Daskalakis, D. M. Blumberger, K. Kay, A. Aloysi, E. M. Gordon, M. T. Bhati, N. Williams, J. D. Power, B. Zebley, L. Grosenick, F. M. Gunning, C. Liston (2024).

Frontostriatal salience network expansion in individuals in depression

Nature

S. R. Unda, L. E. Pomeranz, R. Marongiu, X. Yu, L. Kelly, G. Hassanzadeh, H. Molina, G. Vaisey, P. Wang, J. P. Dyke, E. K. Fung, L. Grosenick, R. Zirkel, A. M. Antoniazzi, S. Norman, C. Liston, C. Schaffer, N. Nishimura, S. A. Stanley, J. M. Friedman, M. G. Kaplitt (2024).

Bidirectional regulation of motor circuits using magnetogenetic gene therapy

Science Advances

A. M. Buch, C. Liston, L. Grosenick (2024).

Simple and scalable algorithms for cluster-aware precision medicine

Artificial Intelligence and Statistics (AISTATS)

K. Dunlop, L. Grosenick, J. Downar, F. Vila-Rodriguez, F. M. Gunning, Z. J. Daskalakis, D. M. Blumberger, C. Liston (2024).

Dimensional and categorical solutions to parsing depression heterogeneity in a large single-site sample

Biological Psychiatry

2023

R. N. Fetcho, B. S. Hall, D. J. Estrin, A. P. Walsh, P. J. Schuette, K. Kaminsky, A. Singh, J. Roshgodal, C. C. Bavley, V. Nadkarni, S. Antigua, T. N. Huynh, L. Grosenick, C. Carthy, L. Komer, A. Adhikari, F. S. Lee, A. M. Rajadhyaksha, C. Liston (2023).

Regulation of social interaction in mice by a frontostriatal circuit modulated by established hierarchical relationships

Nature Communications

A. M. Buch, P. E. Vértes, J. Seidlitz, S. H. Kim, L. Grosenick, C. Liston (2023).

Molecular and network-level mechanisms explaining individual differences in autism spectrum disorder

Nature Neuroscience

2022

K. Dunlop, L. Grosenick, J. Downar, F. Vila-Rodriguez, F. Gunning, Z. Daskalakis, D. M. Blumberger, C. Liston (2022).

Assessing the generalizability and stability of biologically-based subtypes of depression

Neuropharmacology

A. M. Buch, C. Liston, L. Grosenick (2022).

Hierarchically clustered PCA and CCA via a convex clustering penalty

arXiv

N. Solomonov, D. Kanellopoulos, L. Grosenick, V. Wilkins, R. Goldman, S. Ritholtz, A. Falk, F. M. Gunning (2022).

CopeNYP: a brief remote psychological intervention reduces health care workers' depression and anxiety symptoms during COVID-19 pandemic

World Psychiatry

2019

L. Grosenick, T. C. Shi, F. M. Gunning, M. J. Dubin, J. Downar, C. Liston (2019).

Functional and optogenetic approaches to discovering stable subtype-specific circuit mechanisms in depression

Biological Psychiatry: Cognitive Neuroscience and Neuroimaging

A. S. Andalman, V. M. Burns, M. Lovett-Barron, M. Broxton, B. Poole, S. J. Yang, L. Grosenick, T. N. Lerner, R. Chen, T. Benster, P. Mourrain, K. Rajan, K. Deisseroth (2019).

Neuronal dynamics regulating brain and behavioral state transitions

Cell

R. N. Moda-Sava, M. H. Murdock, P. K. Parekh, R. N. Fetcho, B. S. Huang, T. N. Huynh, J. Witztum, D. C. Shaver, D. L. Rosenthal, E. J. Alway, K. Lopez, (2019).

Sustained rescue of prefrontal circuit dysfunction by antidepressant-induced spine formation

Science

S. Aimon, T. Katsuki, T. Jia, L. Grosenick, M. Broxton, K. Deisseroth, T. J. Sejnowski, R. J. Greenspan (2019).

Fast near-whole-brain imaging in adult Drosophila during responses to stimuli and behavior

PLoS Biology

2018

S. J. Reed, C. K. Lafferty, J. A. Mendoza, A. K. Yang, T. J. Davidson, L. Grosenick, K. Deisseroth, J. P. Britt (2018).

Coordinated reductions in excitatory input to the nucleus accumbens underlie food consumption

Neuron

T. N. Huynh, E. Santini, E. Mojica, A. E. Fink, B. S. Hall, R. N. Fetcho, L. Grosenick, K. Deisseroth, J. E. LeDoux, C. Liston, E. Klann (2018).

Extinction of auditory threat memory triggers activation of p70 S6 kinase 1 in the basolateral nucleus of the amygdala

Molecular Psychiatry

T. N. Huynh, E. Santini, E. Mojica, A. E. Fink, B. S. Hall, R. N. Fetcho, L. Grosenick, K. Deisseroth, J. E. LeDoux, C. Liston, E. Klann (2018).

Activation of a novel p70 S6 kinase 1-dependent intracellular cascade in the basolateral nucleus of the amygdala is required for the acquisition of extinction memory

Molecular Psychiatry

S. Aimon, T. Katsuki, T. Jia, L. Grosenick, M. Broxton, K. Deisseroth, T. J. Sejnowski, R. J. Greenspan (2018).

Fast near-whole brain imaging in adult Drosophila during responses to stimuli and behavior

bioRxiv

2017

A. T. Drysdale, L. Grosenick, J. Downar, K. Dunlop, F. Mansouri, Y. Meng, R. N. Fetcho, B. Zebley, D. J. Oathes, A. Etkin, A. F. Schatzberg (2017).

Resting-state connectivity biomarkers define neurophysiological subtypes of depression

Nature Medicine

L. Grosenick, M. Broxton, C. K. Kim, C. Liston, B. Poole, S. Yang, A. Andalman, E. Scharff, N. Cohen, O. Yizhar, C. Ramakrishnan (2017).

Identification of cellular-activity dynamics across large tissue volumes in the mammalian brain

bioRxiv

2016

A. L. Falkner, L. Grosenick, T. J. Davidson, K. Deisseroth, D. Lin (2016).

Hypothalamic control of male aggression-seeking behavior

Nature Neuroscience

E. A. Ferenczi, K. A. Zalocusky, C. Liston, L. Grosenick, M. R. Warden, D. Amatya, K. Katovich, H. Mehta, B. Patenaude, C. Ramakrishnan, P. Kalanithi, A. Etkin, B. Knutson, G. H. Glover, K. Deisseroth (2016).

Prefrontal cortical regulation of brainwide circuit dynamics and reward-related behavior

Science

2015

R. Tomer, M. Lovett-Barron, I. Kauvar, A. Andalman, V. M. Burns, S. Sankaran, L. Grosenick, M. Broxton, S. Yang, K. Deisseroth (2015).

SPED light sheet microscopy: fast mapping of biological system structure and function

Cell

K. L. Montgomery, A. J. Yeh, J. S. Ho, V. Tsao, S. Mohan Iyer, L. Grosenick, E. A. Ferenczi, Y. Tanabe, K. Deisseroth, S. L. Delp, A. S. Poon (2015).

Wirelessly powered, fully internal optogenetics for brain, spinal and peripheral circuits in mice

Nature Methods

J. S. Ho, Y. Tanabe, S. M. Iyer, A. J. Christensen, L. Grosenick, K. Deisseroth, S. L. Delp, A. S. Poon (2015).

Self-tracking energy transfer for neural stimulation in untethered mice

Physical Review Applied

L. Grosenick, J. H. Marshel, K. Deisseroth (2015).

Closed-loop and activity-guided optogenetic control

Neuron

2014

N. Cohen, S. Yang, A. Andalman, M. Broxton, L. Grosenick, K. Deisseroth, M. Horowitz, M. Levoy (2014).

Enhancing the performance of the light field microscope using wavefront coding

Optics Express

L. E. Fenno, J. Mattis, C. Ramakrishnan, M. Hyun, S. Y. Lee, M. He, J. Tucciarone, A. Selimbeyoglu, A. Berndt, L. Grosenick, K. A. Zalocusky (2014).

INTRSECT: single-component targeting of cells using multiple-feature Boolean logic

Nature Methods

L. A. Gunaydin, L. Grosenick, J. C. Finkelstein, I. V. Kauvar, L. E. Fenno, A. Adhikari, S. Lammel, J. J. Mirzabekov, R. D. Airan, K. A. Zalocusky, K. M. Tye (2014).

Natural neural projection dynamics underlying social behavior

Cell

G. I. Allen, L. Grosenick, J. Taylor (2014).

A generalized least-square matrix decomposition

Journal of the American Statistical Association

2013

M. Broxton, L. Grosenick, S. Yang, N. Cohen, A. Andalman, K. Deisseroth, M. Levoy (2013).

Wave optics theory and 3-D deconvolution for the light field microscope

Optics Express

L. Grosenick, B. Klingenberg, K. Katovich, B. Knutson, J. E. Taylor (2013).

Interpretable whole-brain prediction analysis with GraphNet

NeuroImage

K. Chung, J. Wallace, S. Y. Kim, S. Kalyanasundaram, A. S. Andalman, T. J. Davidson, J. J. Mirzabekov, K. A. Zalocusky, J. Mattis, A. K. Denisin, S. Pak, H. Bernstein, C. Ramakrishnan, L. Grosenick, V. Gradinaru, K. Deisseroth (2013).

Structural and molecular interrogation of intact biological systems

Nature

2012

H. Monajemi, (2012).

Deterministic matrices matching the compressed sensing phase transitions of Gaussian random matrices

PNAS

P. Anikeeva, A. S. Andalman, I. Witten, M. Warden, I. Goshen, L. Grosenick (2012).

Optetrode: a multichannel readout for optogenetic control in freely moving mice

Nature Neuroscience

2011

K. M. Tye, R. Prakash, S. Y. Kim, L. E. Fenno, L. Grosenick, H. Zarabi, K. R. Thompson, V. Gradinaru, C. Ramakrishnan, K. Deisseroth (2011).

Amygdala circuitry mediating reversible and bidirectional control of anxiety

Nature

2008

D. K. Wong, L. Grosenick, E. T. Uy, M. Perreau Guimaraes, C. G. Carvalhaes, P. Desain, P. Suppes (2008).

Quantifying inter-subject agreement in brain-imaging analyses

NeuroImage

2007

C. A. Flanagan, C. C. Chen, M. Coetsee, S. Mamputha, K. E. Whitlock, N. Bredenkamp, L. Grosenick, R. D. Fernald, N. Illing (2007).

Expression, Structure, Function, and Evolution of Gonadotropin-Releasing Hormone (GnRH) Receptors GnRH-R1SHS and GnRH-R2PEY in the Teleost, Astatotilapia burtoni

Endocrinology

L. Grosenick, T. S. Clement, R. D. Fernald (2007).

Fish can infer social rank by observation alone

Nature